Conclusion: The ideal CXL procedure should be… effective, safe, and standardized and involve minimal patient discomfort and recovery time. Improved safety and patient benefits accrue when the epithelium is not disrupted. A highly effective [epithelium-on-EpiSmart] technique fulfilling these requirements would be a… preferable protocol.
Corneal Cross-Linking: The Science Beyond the Myths and Misconceptions
Roy S Rubinfeld, MD, MA; Ciro Caruso, MD; and Carmine Ostacolo, PharmD